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Medical Research Journal Article 2009

Transfusion-related mortality: the ongoing risks of allogeneic blood transfusion and the available strategies for their prevention

Vamvakas EC, Blajchman MA

Blood

Summary

Authoritative review cataloguing the full spectrum of transfusion-related adverse events including TRALI, TACO, hemolytic reactions, immunomodulation, and infection. Establishes that transfusion carries meaningful residual risk even in modern medicine.

Key Excerpts

Allogeneic blood transfusion is now the most common procedure performed in hospitalized patients, yet it continues to carry non-negligible risks of adverse reactions, some of which are fatal.

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